Global Entry vs. TSA PreCheck are both government programs designed to expedite airport security and customs processes, but they serve different travel needs. TSA PreCheck is ideal for domestic travelers, offering faster security screening at U.S. airports. Global Entry, on the other hand, includes TSA PreCheck benefits but also provides expedited customs processing for international travelers returning to the U.S. While TSA PreCheck is more budget-friendly at $78, Global Entry costs $100 but offers additional international travel perks. Choosing between the two depends on your travel frequency, destinations, and desired convenience.